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Ultram is a centrally-acting analgesic, used for treating moderate to moderately severe pain. The drug has a wide range of applications, including treatment for restless leg syndrome, acid reflux, and fibermyosis. Ultram is used similarly to codeine, to treat moderate to moderately severe pain and most types of neuralgia, including trigeminal neuralgia. Ultram is somewhat pharmacologically similar to levorphanol (albeit with much lower µ-agonism), as both opioids are also NMDA-antagonists which also have SNRI activity.
Ultram Side Effects
The most commonly reported adverse drug reactions are nausea, vomiting, memory loss, sweating and constipation. Drowsiness is reported, although it is less of an issue than for non-synthetic opioids. Respiratory depression, a common side-effect of most opioids, is not clinically significant in normal doses.
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Soma is a muscle relaxer that works by blocking pain sensations between the nerves and the brain. Soma is used together with rest and physical therapy to treat injuries and other painful musculoskeletal conditions. The drug is is a colorless, crystalline powder, having a mild characteristic odor and a bitter taste. It is slightly soluble in water and freely soluble in alcohol, chloroform and acetone. It had been developed by Dr. Frank M. Berger at Wallace Laboratories and had been named carisoprodol (trade name Soma). Soma has a rapid, 30 minute onset of action, with the aforementioned effects lasting for approximately 2–6 hours. It is metabolized in the liver via the cytochrome P450 oxidase isozyme CYP2C19, excreted by the kidneys and has an approximate 8 hour half-life.
Soma Side Effects
The usual dose of 350 mg is unlikely to engender prominent side effects other than somnolence. The medication is well tolerated and without adverse effects in the majority of patients for which it is indicated. In some patients however, and/or early in therapy, Soma can have the full spectrum of sedative side effects and can impair the patient’s ability to operate a firearm, motorcycle, and other machinery of various types especially when taken with medications containing alcohol, in which case an alternative medication would be considered. The intensity of the side effects of Soma tends to lessen as therapy continues, as is the case with many other drugs.
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Human Growth Hormone is a protein-based poly-peptide hormone. It stimulates growth and cell reproduction and regeneration. Human Growth Hormone is the controlling hormone of many functions and benefits associated with youth, such as vitality, smooth skin, energy and resilience. HGH is naturally produced in the pituitary gland of the brain. As people move past age 30, natural levels of HGH drop off dramatically, about 14% per decade. Lower levels of HGH are associated with the aging process. As HGH levels continue to drop, the aging process accelerates.
Effects of Human Growth Hormone
In addition to increasing height in children and adolescents, human growth hormone has many other effects on the body:
- Increases calcium retention, and strengthens and increases the mineralization of bone
- Increases muscle mass through sarcomere hyperplasia
- Promotes lipolysis
- Increases protein synthesis
- Stimulates the growth of all internal organs excluding the brain
- Plays a role in fuel homeostasis
- Reduces liver uptake of glucose
- Promotes gluconeogenesis in the liver
- Contributes to the maintenance and function of pancreatic islets
- Stimulates the immune system
Human Growth Hormone and Bodybuilding
Human Growth Hormone (HGH) has been used by body builders for years to promote physical enhancement. Normally, after puberty, your body stops growing new muscle cells. The number of muscle cells you have for the rest of your life is genetic, and the most you can do is increase the size of these cells through weight training or steroids. However, by using HGH, you can actually grow new muscle cells. This allows you to reverse genetic dispositions and achieve an ideal muscle density. HGH increases lean body mass, shortens recovery time between workouts, and enhances overall performance. HGH strengthens joints and ligaments and heals damaged tissue.
Human Growth Hormone and Weight Loss
Human Growth Hormone works by increasing the amount of IGF-1 that a person’s liver excretes. IGF-1 prevents insulin from transporting glucose to cells. Normally, after you eat, your pancreas releases the amount of insulin necessary to transform carbohydrates into glucose. Your body then stores this glucose in fat cells and uses it for energy. HGH induced IGF-1 prevents insulin from storing this glucose in cells, therefore forcing your body to burn fat for energy.
Normally, a person’s body uses all of their glucose for energy before seeking that energy from their fat reserves. Human growth hormone forces your body to seek energy from the fat reserves first. This results in significant weight loss.
Anti-aging Human Growth Hormone
Claims for Human Growth Hormone as an anti-aging treatment date back to 1990 when the New England Journal of Medicine published a study wherein HGH was used to treat men over 60. At the conclusion of the study, all the men showed statistically significant increases in lean body mass and bone mineral, while the control group did not. The authors of the study noted that these improvements were the opposite of the changes that would normally occur over a 10- to 20-year aging period. This has led to organizations such as American Academy of Anti-Aging Medicine promoting the use of this hormone as an anti-aging agent.